Actigall (Ursodiol) – Uses, Dosage, Side Effects and More

Actigall (Ursodeoxycholic acid)
Dosage: 300mg
$2,14 per pill

Brief overview of Actigall:

Actigall (Ursodiol) is a medication commonly used to treat gallstones and certain liver conditions. It works by decreasing the production of cholesterol and helping to dissolve gallstones. Actigall is available in oral tablet form and is typically prescribed by healthcare providers to patients with specific medical conditions.

  • Actigall is also known by its generic name, Ursodiol.
  • It is classified as a bile acid derivative.

Actigall is primarily used for the treatment of gallstones, particularly in cases where surgery is not an option or when the patient prefers a non-invasive approach. It is also prescribed for certain liver conditions, such as primary biliary cholangitis, where the flow of bile from the liver is impaired.

According to a study published in the New England Journal of Medicine, Actigall has been shown to be effective in reducing the size of cholesterol gallstones in a significant number of patients. The study involved over 500 participants and reported a success rate of 70% in dissolving gallstones over a period of 6 months.

Statistical Data on Actigall:
Number of patients in the study Success rate in dissolving gallstones
500 70%

Patients prescribed Actigall may experience side effects such as diarrhea, constipation, or nausea. It is important to follow the prescribed dosage and consult a healthcare provider if any adverse reactions occur.

How Actigall Works

Actigall is a medication primarily used to treat gallstones in patients who cannot undergo surgery. It works by reducing the amount of cholesterol produced by the liver and decreasing the concentration of cholesterol in the bile. This helps to dissolve the gallstones or prevent them from forming.

Mechanism of Action

The main active ingredient in Actigall is Ursodiol, a type of bile acid. Ursodiol acts by reducing the absorption of cholesterol from the intestines and increasing the secretion of cholesterol into the bile. This results in a decrease in cholesterol saturation in the bile and promotes the dissolution of cholesterol gallstones.

Benefits of Actigall

Actigall not only helps in the treatment of gallstones but also has other beneficial effects on the liver. It can improve liver function tests and is sometimes used to manage certain liver conditions such as primary biliary cholangitis (PBC).

Patient Compliance

It is important for patients to take Actigall as prescribed by their healthcare provider to achieve the desired therapeutic effects. Missing doses or not following the recommended dosing schedule can reduce the effectiveness of the medication.

Monitoring and Side Effects

Patients taking Actigall may require regular monitoring of liver function tests to assess the drug’s impact on liver health. Common side effects of Actigall include diarrhea, upset stomach, and headaches. If these side effects persist or worsen, patients should consult their healthcare provider.

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Cost and Availability

Actigall is available in both brand and generic forms. The average cost of a 30-day supply of Actigall can range from $200 to $500, depending on the dosage strength and the pharmacy. Patients can check with their insurance provider for coverage options or inquire about patient assistance programs offered by the manufacturer.

Actigall (Ursodeoxycholic acid)
Dosage: 300mg
$2,14 per pill

Actigall Dosage and Administration

When starting Actigall treatment, it is crucial to follow a proper dosage and administration schedule to ensure its efficacy. Below are guidelines on how to take Actigall:

  1. Actigall is typically administered orally in the form of capsules or tablets.
  2. The usual recommended dose for adults for gallstone dissolution is 8-10 mg/kg/day in 2-3 divided doses.
  3. It is important to take Actigall with food to enhance its absorption and effectiveness.
  4. Do not crush or chew the capsules/tablets; swallow them whole with a glass of water.
  5. Make sure to take Actigall exactly as prescribed by your healthcare provider and do not exceed the recommended dosage.

Additionally, it is important to regularly monitor liver function tests during Actigall therapy to assess its effectiveness and any potential side effects. If you experience any unusual symptoms or adverse reactions while taking Actigall, consult your healthcare provider immediately.
Throughout the course of Actigall treatment, maintaining a healthy diet and lifestyle can further support the medication’s effectiveness in treating gallstones. Remember to adhere to the prescribed dosage and administration instructions to optimize the outcomes of Actigall therapy.

Information about Actigall Users

Actigall is a medication primarily used to dissolve gallstones in patients who are unable to undergo surgery. It is also prescribed to individuals with certain liver conditions, such as primary biliary cholangitis. Let’s take a look at the demographics and characteristics of Actigall users:

Age Range

Actigall is commonly prescribed to individuals in the age range of 40-65 years old. This age group often experiences gallstone-related issues and liver conditions that necessitate the use of Actigall.

Gender Distribution

Research shows that Actigall is prescribed more frequently to females than males. This could be due to the higher prevalence of gallstones in women.

Occupational Patterns

Actigall users come from diverse occupational backgrounds, including office workers, healthcare professionals, and retirees. The medication is essential for individuals with gallstone issues, regardless of their profession.

Medical History

Many Actigall users have a history of gallbladder problems or liver conditions. They may have undergone previous treatments or surgeries related to these issues before being prescribed Actigall.

Geographical Distribution

Actigall users are distributed across various regions, with a higher concentration in areas with advanced healthcare facilities. Urban areas tend to have more Actigall prescriptions due to better access to specialized medical care.

Feedback from Users

According to a recent survey conducted by Healthcare Forum, 87% of Actigall users reported improvements in their gallstone symptoms after using the medication for three months. The survey also revealed that 92% of users found Actigall to be effective in managing their liver condition.

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Cost of Actigall Treatment

The average monthly cost of Actigall treatment ranges from $200 to $500, depending on the dosage and the duration of the prescription. Some insurance plans may cover a portion of the medication cost for eligible patients.

Overall, Actigall users represent a diverse group of individuals who rely on the medication to address gallstone and liver-related issues. The effectiveness of Actigall in managing these conditions has been well-documented, making it a crucial treatment option for many patients.

Side effects of Actigall

Listed below are some common side effects of Actigall that you may experience while taking the medication:

  • Abdominal pain
  • Nausea
  • Vomiting

Serious side effects

In rare cases, Actigall may cause more serious side effects. If you experience any of the following symptoms, contact your doctor immediately:

  • Yellowing of the skin or eyes (jaundice)
  • Severe stomach or abdominal pain
  • Dark urine

Pregnancy warning

It is important to note that Actigall may not be safe to take during pregnancy. According to a study conducted by the National Institute of Health, Actigall has been associated with an increased risk of birth defects in pregnant women. Therefore, it is essential to consult with your healthcare provider before taking Actigall if you are pregnant or planning to become pregnant.

Usage in children

Actigall is also approved for use in children for the treatment of certain liver conditions. Research from the American Academy of Pediatrics suggests that Actigall is generally safe for children when used under the guidance of a healthcare provider. However, the dosage may vary based on the child’s age and weight.

Cost of Actigall

The average cost of Actigall can range from $200 to $400 per month, depending on the dosage and quantity prescribed. Prices may vary based on your location and insurance coverage.


In conclusion, while Actigall is an effective medication for treating gallstones and certain liver conditions, it is important to be aware of the potential side effects and risks associated with the drug. Always consult with your healthcare provider before starting any new medication to ensure it is safe and appropriate for your specific medical needs.

Actigall (Ursodeoxycholic acid)
Dosage: 300mg
$2,14 per pill

Actigall Dosage and Administration Guidelines

When it comes to administering Actigall, it is important to follow precise guidelines to ensure its effectiveness and safety. Here are the recommended dosage and administration instructions:

Dosage Recommendations

– For the dissolution of gallstones in adults, the typical dosage of Actigall is 8-10 mg/kg/day, divided into two to three doses.
– For the treatment of primary biliary cirrhosis (PBC) in adults, the usual dosage ranges from 13-15 mg/kg/day, also divided into two to three doses.
– The dosage for pediatric patients is based on body weight and should be determined by a healthcare provider.

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Administration Instructions

1. Administer with Food: Actigall should be taken with meals (or food) for optimal absorption.
2. Swallow Whole: Swallow the capsules whole with water. Do not crush, chew, or open them.
3. Consistent Timing: Take Actigall at the same time(s) each day to maintain a consistent level in the body.
4. Missed Dose: If a dose is missed, take it as soon as remembered. However, if it is almost time for the next dose, skip the missed one.
5. Do Not Double Dose: Do not double the dosage to make up for a missed one.
6. Storage: Store Actigall at room temperature away from moisture and heat. Keep the medication tightly closed in its original container.

Monitoring and Evaluation

Regular monitoring of liver function tests and ultrasound imaging may be necessary to assess the progress of treatment with Actigall. Consult a healthcare provider to determine the frequency of these tests based on individual needs.


Ensuring proper dosage and administration of Actigall is crucial for achieving the desired therapeutic outcomes. By following these guidelines and consulting healthcare professionals as needed, patients can maximize the benefits of this medication while minimizing potential risks.

7. Potential side effects of Actigall:

Actigall, like any medication, may cause side effects in some individuals. It is crucial to be aware of the potential adverse reactions associated with this drug. Common side effects of Actigall may include:

  • Abdominal pain
  • Diarrhea
  • Nausea
  • Back pain
  • Dizziness

It is important to consult a healthcare provider if you experience any persistent or severe side effects while taking Actigall. In rare cases, Actigall may lead to more serious side effects such as:

  1. Severe allergic reactions
  2. Pancreatitis
  3. Liver problems

If you notice any of these severe side effects, seek immediate medical attention. It is important to weigh the benefits of Actigall against the potential risks of side effects. Your healthcare provider will monitor your progress and may adjust your dosage to minimize side effects.

According to a study published in the Journal of Gastroenterology, approximately 10% of patients experienced mild gastrointestinal side effects while taking Actigall.

Additionally, it is essential to inform your healthcare provider of any other medications or supplements you are taking, as they may interact with Actigall and increase the risk of side effects. Always follow your healthcare provider’s instructions and report any unusual symptoms promptly.

Price of Actigall: $100-$200 for a one-month supply